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A White Light‐Emitting Quantum Dot Complex for Single Particle Level Interaction with Dopamine Leading to Changes in Color and Blinking Profile
Author(s) -
Pramanik Sabyasachi,
Bhandari Satyapriya,
Pan Uday Narayan,
Roy Shilaj,
Chattopadhyay Arun
Publication year - 2018
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201800323
Subject(s) - quantum dot , white light , particle (ecology) , dopamine , materials science , optoelectronics , physics , nanotechnology , optics , psychology , neuroscience , oceanography , geology
Abstract The interaction of the neurotransmitter dopamine is reported with a single particle white light‐emitting (WLE) quantum dot complex (QDC). The QDC is composed of yellow emitting ZnO quantum dots (Qdots) and blue emitting Zn(MSA) 2 complex (MSA = N ‐methylsalicylaldimine) synthesized on their surfaces. Sensing is achieved by the combined changes in the visual luminescence color from white to blue, chromaticity color coordinates from (0.31, 0.33) to (0.24, 0.23) and the ratio of the exponents (α on /α off ) of on/off probability distribution (from 0.24 to 3.21) in the blinking statistics of WLE QDC. The selectivity of dopamine toward ZnO Qdots, present in WLE QDC, helps detect ≈13 dopamine molecules per Qdot. Additionally, the WLE QDC exhibits high sensitivity, with a limit of detection of 3.3 × 10 −9 m (in the linear range of 1–100 × 10 −9 m ) and high selectivity in presence of interfering biological species. Moreover, the single particle on–off bilking statistics based detection strategy may provide an innovative way for ultrasensitive detection of analytes.