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Single Molecule Manipulation: Pick‐and‐Place Assembly of Single Microtubules (Small 32/2017)
Author(s) -
Tarhan Mehmet Cagatay,
Yokokawa Ryuji,
Jalabert Laurent,
Collard Dominique,
Fujita Hiroyuki
Publication year - 2017
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201770172
Subject(s) - microtubule , bridging (networking) , kinesin , nanotechnology , tweezers , optical tweezers , materials science , biophysics , physics , computer science , optics , biology , microbiology and biotechnology , computer network
In article number 1701136 , by Mehmet Cagatay Tarhan and co‐workers, MEMS tweezers allow the manipulation of biological samples such as individual microtubules. Bridging between parallel walls, these 25 nm diameter tubular structures can be picked by sharp protruding tips. Motorized stage positions target the location with high precision to place the microtubules carried between the tips. Repeating this pick‐and‐place cycle, a multilayered microtubule network is generated for kinesin motionin selected directions.