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2D Materials: Size Effect on the Cytotoxicity of Layered Black Phosphorus and Underlying Mechanisms (Small 32/2017)
Author(s) -
Zhang Xuejiao,
Zhang Ziming,
Zhang Siyu,
Li Dengyu,
Ma Wei,
Ma ChuanXin,
Wu Fengchang,
Zhao Qing,
Yan Qingfeng,
Xing Baoshan
Publication year - 2017
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201770171
Subject(s) - cytotoxicity , black phosphorus , phosphorus , intracellular , cell size , membrane , chemistry , materials science , biophysics , chemical engineering , nanotechnology , biochemistry , in vitro , microbiology and biotechnology , organic chemistry , biology , optoelectronics , engineering
Bulk black phosphorus (BP) crystals are synthesized and exfoliated into layered BP with different lateral size and thickness, in article number 1701210 by Qing Zhao, Qingfeng Yan, and Baoshan Xing, and co‐workers. The results of real‐time cell analysis (RTCA) display a concentration‐, size‐, and cell type‐dependent cytotoxicity of layered BP. The cytotoxicity originates from the intracellular ROS generation and cell membrane disruption, but only the latter is related to size effect.