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DNA Nanostructures: Tetrahedral DNA Nanostructure: A Potential Promoter for Cartilage Tissue Regeneration via Regulating Chondrocyte Phenotype and Proliferation (Small 12/2017)
Author(s) -
Shao Xiaoru,
Lin Shiyu,
Peng Qiang,
Shi Sirong,
Wei Xueqin,
Zhang Tao,
Lin Yunfeng
Publication year - 2017
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201770070
Subject(s) - chondrocyte , cartilage , regeneration (biology) , microbiology and biotechnology , phenotype , nanostructure , dna , materials science , nanotechnology , chemistry , biology , anatomy , biochemistry , gene
A tetrahedral DNA nanostructure (TDN), a novel type of DNA nanomaterials, is able to regulate chondrocyte phenotype and promote chondrocyte proliferation, as presented in article number 1602770 by Yunfeng Lin and co‐workers. The regulation of cell phenotype is related with down‐regulating the Notch signaling pathway. This discovery sheds light on the potential of TDNs in future medicine, especially cartilage regeneration.