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Magnetic Nanoparticles: High‐Throughput, Protein‐Targeted Biomolecular Detection Using Frequency‐Domain Faraday Rotation Spectroscopy (Small 12/2017)
Author(s) -
Murdock Richard J.,
Putnam Shawn A.,
Das Soumen,
Gupta Ankur,
Chase Elyse D. Z.,
Seal Sudipta
Publication year - 2017
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201770066
Subject(s) - faraday effect , biomolecule , magnetic nanoparticles , nanoparticle , spectroscopy , materials science , magnetic field , conjugated system , nanotechnology , characterization (materials science) , rotation (mathematics) , chemical physics , nuclear magnetic resonance , chemistry , physics , computer science , polymer , quantum mechanics , artificial intelligence
In article number 1602862, Shawn A. Putnam and co‐workers, revisiting a 170 year old magneto‐optical phenomenon, reveal a fast, sensitive, and versatile medical test. Polarized light interacts with functionalized magnetic nanoparticles in the biomolecule characterization method called fd‐FRS (frequency‐domain Faraday Rotation Spectroscopy). Alternating magnetic fields induce particle rotation and realignment with the magnetic field – a process dependent on the size, conformation, and density of the conjugated biomolecules.