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Polymer Nanoparticles: Multifunctional Conjugated Polymer Nanoparticles for Image‐Guided Photodynamic and Photothermal Therapy (Small 3/2017)
Author(s) -
Feng Guangxue,
Fang Yuan,
Liu Jie,
Geng Junlong,
Ding Dan,
Liu Bin
Publication year - 2017
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201770014
Subject(s) - photothermal therapy , singlet oxygen , conjugated system , photodynamic therapy , nanoparticle , polymer , materials science , nanotechnology , in vivo , chemistry , oxygen , organic chemistry , microbiology and biotechnology , composite material , biology
Multifunctional conjugated polymer nanoparticles (CPNs) are developed for image‐guided phototherapy by D. Ding, B. Liu, and co‐workers in article number 1602807. Under proper light irradiation, these CPNs display bright red fluorescence, efficient singlet oxygen generation and excellent photothermal conversion abilities. With affibody decoration, these CPNs show excellent tumor targeting and synergistic therapeutic efficacy through the cooperation of photodynamic and photothermal therapy both in vitro and in vivo.