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Carbon Nanotubes: Crucial Role of P2X 7 Receptor in Regulating Exocytosis of Single‐Walled Carbon Nanotubes in Macrophages (Small 43/2016)
Author(s) -
Cui Xuejing,
Wan Bin,
Yang Yu,
Ren Xiaomin,
Guo LiangHong,
Zhang Hui
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670226
Subject(s) - exocytosis , carbon nanotube , secretion , microbiology and biotechnology , nanotechnology , materials science , chemistry , biology , biochemistry
The exocytosis and underlying mechanism of single‐walled carbon nanotubes (SWCNTs) in macrophages is revealed by B. Wan, L.‐H. Guo, and co‐workers on page 5998. Exocytosis of SWCNTs is initiated by the activation of the P2X 7 receptor, which accounts for the lysosomal secretion pathway as a potential mechanism for cells to repel SWCNTs. The cover image shows microtubules providing orbits for the exocytosis of SWCNTs‐containing lysosomes.