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Drug Delivery: Theranostic Upconversion Nanobeacons for Tumor mRNA Ratiometric Fluorescence Detection and Imaging‐Monitored Drug Delivery (Small 43/2016)
Author(s) -
Ding Qianwen,
Zhan Qiuqiang,
Zhou Xiaoming,
Zhang Tao,
Xing Da
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670221
Subject(s) - nanoprobe , drug delivery , photon upconversion , fluorescence , fluorescence lifetime imaging microscopy , messenger rna , materials science , nanotechnology , cancer research , chemistry , nanoparticle , luminescence , medicine , optoelectronics , biochemistry , optics , gene , physics
On page 5944, T. Zhang, D. Xing, and co‐workers utilize upconversion luminescent materials to construct a new theranostic nanoprobe. This probe detects and images specific tumor‐related mRNA and monitors target‐triggered therapeutic drug release according to the mRNA expression level under near infrared (NIR) irradiation.
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