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Breast Cancer Therapy: Defined Host–Guest Chemistry on Nanocarbon for Sustained Inhibition of Cancer (Small 42/2016)
Author(s) -
Ostadhossein Fatemeh,
Misra Santosh K.,
Mukherjee Prabuddha,
Ostadhossein Alireza,
Daza Enrique,
Tiwari Saumya,
Mittal Shachi,
Gryka Mark C.,
Bhargava Rohit,
Pan Dipanjan
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670216
Subject(s) - supramolecular chemistry , in vivo , chemistry , nanotechnology , in vitro , cancer , breast cancer , combinatorial chemistry , biochemistry , materials science , organic chemistry , molecule , biology , medicine , microbiology and biotechnology
A theranostic, enzymatically biodegradable nanoplatform based on luminescent carbon particles decorated with cucurbit[6]uril is introduced for enhancing the solubility of niclosamide, a STAT‐3 inhibitor. On page 5845, D. Pan and co‐workers reveal that, overall, the supramolecular chemistry on nanocarbon acts as a novel arsenal for STAT‐3 inhibition in vitro and in vivo and provides signature intracellular tracking.