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Allergen Arrays: Click‐Chemistry Based Allergen Arrays Generated by Polymer Pen Lithography for Mast Cell Activation Studies (Small 38/2016)
Author(s) -
Kumar Ravi,
Bonicelli Alice,
SekulaNeuner Sylwia,
Cato Andrew C. B.,
Hirtz Michael,
Fuchs Harald
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670195
Subject(s) - lithography , microfluidics , nanotechnology , fluorescence microscope , allergen , materials science , mast cell , polymer , chemistry , fluorescence , optoelectronics , immunology , allergy , biology , optics , physics , composite material
Microfluidic encapsulated allergen arrays are created by M. Hirtz and co‐workers on page 5330 using polymer pen lithography (PPL). These arrays are utilized in mast cell activation studies on a single cell level. The overall setup enables easy handling of cell suspension, incubation, and read‐out by fluorescence microscopy, allowing immune cell activation screening to be easily adapted for diagnostics and biomedical research.