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Nanocomposites: Nanocomposite Hydrogels as Platform for Cells Growth, Proliferation, and Chemotaxis (Small 35/2016)
Author(s) -
Fiorini Federica,
Prasetyanto Eko Adi,
Taraballi Francesca,
Pandolfi Laura,
Monroy Francisco,
LópezMontero Iván,
Tasciotti Ennio,
De Cola Luisa
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670179
Subject(s) - nanocomposite , chemotaxis , self healing hydrogels , materials science , tissue engineering , nanoparticle , stem cell , mesoporous silica , in vivo , nanotechnology , in vitro , mesoporous material , biomedical engineering , chemistry , microbiology and biotechnology , polymer chemistry , biology , receptor , medicine , biochemistry , catalysis
L. De Cola and co‐workers report a nanocomposite hydrogel able to induce in vitro chemotaxis of stem cells on page 4881. The cover image shows a nanocomposite hydrogel containing mesoporous silica nanoparticles integrated into the polymeric network. The controlled release of SDF‐1α from the hydrogel induced the chemotaxis of stem cells, while the optimal mechanical properties enhanced stem cells proliferation. These attractive properties together with the low inflammatory response in vivo make this hydrogel a promising material for tissue engineering applications.