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Gold Nanoshells: Combined Near Infrared Photothermal Therapy and Chemotherapy Using Gold Nanoshells Coated Liposomes to Enhance Antitumor Effect (Small 30/2016)
Author(s) -
Luo Liyao,
Bian Yanhong,
Liu Yanping,
Zhang Xuwu,
Wang Meili,
Xing Shanshan,
Li Lei,
Gao Dawei
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670150
Subject(s) - nanoshell , photothermal therapy , materials science , liposome , drug delivery , nanotechnology , chitosan , in vivo , photothermal effect , biomedical engineering , nanoparticle , chemistry , medicine , organic chemistry , microbiology and biotechnology , biology
Gold nanoshell coated oleanolic acid liposomes mediating by chitosan (GNOLs), are designed and successfully synthesized for the first time by D. Gao and co‐workers on page number 4103. An excellent near infrared (NIR) photothermal effect, pH‐responsive drug controlled release and tumor targeting properties are demonstrated. By combining NIR photothermal therapy and chemotherapy, the smart drug delivery system exhibits a superior antitumor property in vitro and in vivo.