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Phase‐Transition Nanowires: Protein Recognition by Phase Transition of Aptamer‐Linked Polythiophene Single Nanowire (Small 9/2016)
Author(s) -
Cui Chunzhi,
Park Dong Hyuk,
Choi Hyun,
Joo Jinsoo,
Ahn Dong June
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670045
Subject(s) - nanowire , aptamer , biomolecule , polythiophene , materials science , raman spectroscopy , phase transition , nanotechnology , photoluminescence , molecular recognition , polymer , conjugated system , phase (matter) , conductive polymer , chemistry , optoelectronics , molecule , biology , organic chemistry , quantum mechanics , optics , genetics , physics , composite material
Direct identification of proteins, important but non‐amplifiable biomolecules, is critical in advancing modern biomedicine technologies. J. Joo, D. J. Ahn, and co‐workers explore the phase‐transition phenomenon of conjugated polymer nanowires in response to the presence of protein particles on page 1154. Even a single polythiophene nanowire having capture aptamers functionalized on its surface responds to a specific interaction with target proteins. Such a unique phase‐transition evokes enhancement of photoluminescence and generation of a local resonance Raman signal simultaneously, dramatically corresponding to protein concentration.