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Acoustic Streaming: Probing Cell Deformability via Acoustically Actuated Bubbles (Small 7/2016)
Author(s) -
Xie Yuliang,
Nama Nitesh,
Li Peng,
Mao Zhangming,
Huang PoHsun,
Zhao Chenglong,
Costanzo Francesco,
Huang Tony Jun
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201670031
Subject(s) - microfluidics , bioanalysis , acoustic streaming , nanotechnology , materials science , bubble , cell mechanics , cell , computer science , acoustics , chemistry , physics , biochemistry , cytoskeleton , parallel computing , ultrasonic sensor
An acoustically actuated, bubble‐based technique is developed to investigate the deformability of cells suspended in microfluidic devices. On page 902, measurements of mechanical biomarkers from multiple cells made by T. J. Huang and co‐workers are conducted in a single experiment, and integrated with other bioanalysis and drug‐screening platforms. It is expected that this technique could provide insights for cell biology studies and biophysical cellular diagnosis.