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Long‐Term Real‐Time In Vivo Drug Release Monitoring with AIE Thermogelling Polymer
Author(s) -
Liow Sing Shy,
Dou Qingqing,
Kai Dan,
Li Zibiao,
Sugiarto Sigit,
Yu Chris Yee Yung,
Kwok Ryan Tsz Kin,
Chen Xiaohong,
Wu YunLong,
Ong Seow Theng,
Kizhakeyil Atish,
Verma Navin K.,
Tang Ben Zhong,
Loh Xian Jun
Publication year - 2017
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201603404
Subject(s) - drug delivery , computer science , drug , term (time) , in vivo , nanotechnology , aggregation induced emission , service (business) , materials science , pharmacology , medicine , business , physics , microbiology and biotechnology , quantum mechanics , fluorescence , biology , marketing
A new drug concentration meter is developed . In vivo drug release can be monitored precisely via a self‐indicating drug delivery system consisting of a new aggregation‐induced emission thermoresponsive hydrogel. By taking the advantage of a self‐indicating system, one can easily detect the depletion of drugs, and reinject to maintain a dosage in the optimal therapeutic window.