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Acoustofluidic Rotational Manipulation of Cells and Organisms Using Oscillating Solid Structures
Author(s) -
Ozcelik Adem,
Nama Nitesh,
Huang PoHsun,
Kaynak Murat,
McReynolds Melanie R.,
HannaRose Wendy,
Huang Tony Jun
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201601760
Subject(s) - microchannel , polydimethylsiloxane , enhanced data rates for gsm evolution , oscillation (cell signaling) , transducer , plane (geometry) , computer science , field (mathematics) , microfluidics , nanotechnology , materials science , acoustics , mechanical engineering , physics , chemistry , engineering , telecommunications , mathematics , biochemistry , geometry , pure mathematics
A polydimethylsiloxane microchannel featuring sidewall sharp‐edge structures and bare channels, and a piezoelement transducer is attached to a thin glass slide. When an external acoustic field is applied to the microchannel, the oscillation of the sharp‐edge structures and the thin glass slide generate acoustic streaming flows which in turn rotate single cells and C. elegans in‐plane and out‐of‐plane.