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Functional Photoacoustic Imaging of Gastric Acid Secretion Using pH‐Responsive Polyaniline Nanoprobes
Author(s) -
Li Junwei,
Xiao Hong,
Yoon Soon Joon,
Liu Chengbo,
Matsuura Drew,
Tai Wanyi,
Song Liang,
O'Donnell Matthew,
Cheng Du,
Gao Xiaohu
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201601359
Subject(s) - photoacoustic imaging in biomedicine , christian ministry , chinese academy of sciences , library science , chemistry , medicine , china , physics , philosophy , computer science , theology , political science , optics , law
A stomach functional imaging technique based on photoacoustics achieves noninvasive gastric acid secretory assessment utilizing pH‐responsive polyaniline nanoprobes. A testing protocol mimicking clinical practice is established using a mouse model. After imaging, the nanoprobes are excreted outside the body without inducing systematic toxicity. Further optimization and translation of this technology can help alleviate patients' suffering and side effects.