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Biomimicking Nano‐Micro Binary Polymer Brushes for Smart Cell Orientation and Adhesion Control
Author(s) -
Chen Lina,
Xie Zhuang,
Gan Tiansheng,
Wang Yi,
Zhang Guangzhao,
Mirkin Chad A.,
Zheng Zijian
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201600634
Subject(s) - glycidyl methacrylate , nanotechnology , nano , materials science , polymer , polystyrene , adhesion , computer science , polymer science , composite material , polymerization
A new biomimetic surface named nano‐micro binary polymer brushes is fabricated by large‐area bench‐top dip‐pen nanodisplacement lithography technique. It is composed of gelatin‐modified poly(glycidyl methacrylate) nanolines which are spaced by microstripes of poly( N ‐isopropylacrylamide). Cells are not only adhered and oriented well on the re‐used surface, but also detachable from the surface with well‐preserved extracellular matrix and aligned morphology.