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High‐Resolution Vertical Observation of Intracellular Structure Using Magnetically Responsive Microplates
Author(s) -
Teshima Tetsuhiko,
Onoe Hiroaki,
Tottori Soichiro,
Aonuma Hiroka,
Mizutani Takeomi,
Kamiya Koki,
Ishihara Hirotaka,
Kanuka Hirotaka,
Takeuchi Shoji
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201600339
Subject(s) - confocal , resolution (logic) , nanotechnology , computer science , high resolution , microscope , service (business) , confocal microscopy , materials science , optics , physics , artificial intelligence , remote sensing , geology , business , marketing
A vertical confocal observation system capable of high‐resolution observation of intracellular structure is demonstrated. The system consists of magnet‐active microplates to rotate, incline, and translate single adherent cells in the applied magnetic field. Appended to conventional confocal microscopes, this system enables high‐resolution cross‐sectional imaging with single‐molecule sensitivity in single scanning.