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Molecular Delivery: Rapid, High‐Throughput, and Direct Molecular Beacon Delivery to Human Cancer Cells Using a Nanowire‐Incorporated and Pneumatic Pressure‐Driven Microdevice (Small 46/2015)
Author(s) -
Kim Kyung Hoon,
Kim Jung,
Choi Jong Seob,
Bae Sunwoong,
Kwon Donguk,
Park Inkyu,
Kim Do Hyun,
Seo Tae Seok
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201570278
Subject(s) - nanowire , materials science , nanotechnology , layer (electronics) , microchannel , throughput , microfluidics , computer science , wireless , telecommunications
A nanowire‐incorporated and pneumatic pressure‐driven microdevice for rapid, high‐throughput and direct molecular beacon (MB) delivery is described by I. Park, T. S. Seo, and co‐workers. On page 6215, they show how the microdevice, composed of a manifold layer, a monolithic PDMS membrane, and a nanowire‐patterned microchannel layer, could manipulate cellular movement, so the attachment and detachment from the MB‐functionalized nanowire array is performed in a controllable way to increase MB delivery efficiency.