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Cancer Therapy: Smart Probe for Tracing Cancer Therapy: Selective Cancer Cell Detection, Image‐Guided Ablation, and Prediction of Therapeutic Response In Situ (Small 36/2015)
Author(s) -
Yuan Youyong,
Kwok Ryan T. K.,
Tang Ben Zhong,
Liu Bin
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201570219
Subject(s) - photodynamic therapy , photosensitizer , cancer , cancer cell , in situ , cancer research , ablation , cancer therapy , materials science , pheophorbide a , nanotechnology , biophysics , medicine , chemistry , photochemistry , biology , organic chemistry
A pH‐responsive probe containing tetraphenylsilole with aggregation‐induced emission characteristics and a pheophorbide A photosensitizer with an aggregation‐caused quenching (ACQ) property is developed by B. Z. Tang, B. Liu, and co‐workers. On page 4682, they describe how it can be used for self‐tracking, selective cancer cell imaging, activated photodynamic ablation of cancer cells, and in‐situ prediction of the therapeutic response.