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Biomedical Imaging: Direct Solvent‐Derived Polymer‐Coated Nitrogen‐Doped Carbon Nanodots with High Water Solubility for Targeted Fluorescence Imaging of Glioma (Small 29/2015)
Author(s) -
Wang Yi,
Meng Ying,
Wang Shanshan,
Li Chengyi,
Shi Wei,
Chen Jian,
Wang Jianxin,
Huang Rongqin
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201570171
Subject(s) - nanodot , materials science , fluorescence , glioma , polymer , solvent , in vivo , fluorescence lifetime imaging microscopy , solubility , carbon fibers , nitrogen , photochemistry , nanotechnology , nuclear chemistry , chemistry , organic chemistry , cancer research , medicine , optics , biology , physics , microbiology and biotechnology , composite number , composite material
Polymer‐coated, nitrogen‐doped, carbon nanodots (pN‐CNDs), shown as green/blue particles in the image, are produced by R. Q. Huang and co‐workers via a one‐step direct solvothermal reaction of 1‐methyl‐2‐pyrrolidinone. On page 3575, the pN‐CNDs are shown to expediently enter glioma via blood vessels and mediate glioma fluorescence imaging in vivo with good contrast, via enhanced passive targeting.