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Crystallography: Precise Manipulation and Patterning of Protein Crystals for Macromolecular Crystallography Using Surface Acoustic Waves (Small 23/2015)
Author(s) -
Guo Feng,
Zhou Weijie,
Li Peng,
Mao Zhangming,
Yennawar Neela H.,
French Jarrod B.,
Huang Tony Jun
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201570131
Subject(s) - capillary action , piezoelectricity , materials science , macromolecule , layer (electronics) , transducer , surface acoustic wave , acoustic wave , crystallography , coupling (piping) , substrate (aquarium) , nanotechnology , optics , acoustics , chemistry , composite material , physics , biology , ecology , biochemistry
J. B. French, T. J. Huang, and co‐workers develop a surface acoustic wave method to manipulate protein crystals for macromolecular crystallography. On page 2733, a capillary tube is coupled onto a piezoelectric substrate with a pair of interdigital transducers. When the transducers are turned on, an acoustic field is generated and introduced into the capillary through a thin layer of coupling gel. The micrometersized protein crystals suspended in the capillary will then be manipulated by the acoustic field and aligned into a linear pattern.
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