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Transmission Electron Microscopy: Isotope Substitution Extends the Lifetime of Organic Molecules in Transmission Electron Microscopy (Small 5/2015)
Author(s) -
Chamberlain Thomas W.,
Biskupek Johannes,
Skowron Stephen T.,
Bayliss Peter A.,
Bichoutskaia Elena,
Kaiser Ute,
Khlobystov Andrei N.
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201570027
Subject(s) - transmission electron microscopy , molecule , energy filtered transmission electron microscopy , deuterium , scanning transmission electron microscopy , electron beam induced deposition , electron , chemical physics , electron microscope , materials science , microscopy , nanotechnology , transmission (telecommunications) , chemistry , atomic physics , physics , optics , organic chemistry , computer science , telecommunications , quantum mechanics
Decreasing the energy of the electron beam in transmission electron microscopy (TEM) improves the stability of inorganic molecules, however, organic molecules become surprisingly less stable under these conditions. On page 622, E. Bichoutskaia, U. Kaiser, A. N. Khlobystov, and co‐workers analyse the interactions of the e‐beam with C–H bonds and are able to highlight the low atomic weight of hydrogen as a key issue. Exchanging protium for deuterium resolves the issue and brings atomic‐resolution TEM imaging of individual organic molecules closer to reality.

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