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Nanoporous Carbons Derived from Metal‐Organic Frameworks as Novel Matrices for Surface‐Assisted Laser Desorption/Ionization Mass Spectrometry
Author(s) -
Shih YungHan,
Fu ChienPing,
Liu WanLing,
Lin ChiaHer,
Huang HsiYa,
Ma Shengqian
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201502817
Subject(s) - nanoporous , mass spectrometry , desorption , materials science , ionization , laser , biomolecule , matrix (chemical analysis) , polymer , matrix assisted laser desorption/ionization , soft laser desorption , chemical engineering , nanotechnology , chemistry , organic chemistry , adsorption , chromatography , ion , composite material , physics , optics , engineering
Surface‐assisted laser desorption/ionization mass spectrometry (SALDI‐MS) represents a powerful tool for the analysis of biomolecules, synthetic polymers, and even small organic compounds; its performances largely depend on the type of matrix materials utilized. Here, for the first time the employment of nanoporous carbons derived from metal‐organic frameworks (MOFs) as novel matrices for SALDI‐MS is demonstrated. The nanoporous carbons derived from MOFs not only circumvent the shortcomings of existing matrix materials but also demonstrate much higher efficiency of laser desorption/ionization for various compounds than any other nanoporous carbons reported so far. A new perspective for the development of matrix materials for SALDI‐MS application is therefore provided.