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Hydrogels Constructed from Engineered Proteins
Author(s) -
Li Hongbin,
Kong Na,
Laver Bryce,
Liu Junqiu
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201502429
Subject(s) - self healing hydrogels , nanotechnology , tissue engineering , materials science , protein engineering , chemistry , biomedical engineering , engineering , biochemistry , polymer chemistry , enzyme
Due to their various potential biomedical applications, hydrogels based on engineered proteins have attracted considerable interest. Benefitting from significant progress in recombinant DNA technology and protein engineering/design techniques, the field of protein hydrogels has made amazing progress. The latest progress of hydrogels constructed from engineered recombinant proteins are presented, mainly focused on biorecognition‐driven physical hydrogels as well as chemically crosslinked hydrogels. The various bio‐recognition based physical crosslinking strategies are discussed, as well as chemical crosslinking chemistries used to engineer protein hydrogels, and protein hydrogels' various biomedical applications. The future perspectives of this fast evolving field of biomaterials are also discussed.