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Long‐Range Charge Transport in Adenine‐Stacked RNA:DNA Hybrids
Author(s) -
Li Yuanhui,
Artés Juan M.,
Hihath Joshua
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201502399
Subject(s) - rna , dna , nanoscopic scale , oligonucleotide , charge (physics) , conductance , computational biology , nanotechnology , computer science , biophysics , biology , materials science , genetics , physics , gene , condensed matter physics , quantum mechanics
An extremely important biological component, RNA:DNA can also be used to design nanoscale structures such as molecular wires. The conductance of single adenine‐stacked RNA:DNA hybrids is rapidly and reproducibly measured using the break junction approach. The conductance decreases slightly over a large range of molecular lengths, suggesting that RNA:DNA can be used as an oligonucleotide wire.