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Host–Guest Interaction‐Mediated Construction of Hydrogels and Nanovesicles for Drug Delivery
Author(s) -
Xu XingDong,
Li Xin,
Chen Hongzhong,
Qu Qiuyu,
Zhao Lingzhi,
Ågren Hans,
Zhao Yanli
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201502222
Subject(s) - nanocarriers , drug delivery , self healing hydrogels , computer science , host (biology) , nanotechnology , cytotoxicity , derivative (finance) , doxorubicin , chemistry , combinatorial chemistry , materials science , polymer chemistry , medicine , biology , chemotherapy , biochemistry , business , surgery , in vitro , ecology , finance
Hand‐in‐hand or head‐to‐head : A novel naphthalimide derivative is successfully designed and synthesized, which can self‐assemble to produce hydrogels. When injecting this compound into CB[8] solution, the nanovesicles are obtained with a narrow size distribution. The cytotoxicity assay confirms that doxorubicin‐loaded nanocarriers show therapeutic effects to cancer cells.