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Plasmonic Nanohole Sensor for Capturing Single Virus‐Like Particles toward Virucidal Drug Evaluation
Author(s) -
Jackman Joshua A.,
Linardy Eric,
Yoo Daehan,
Seo Jeongeun,
Ng Wei Beng,
Klemme Daniel J.,
Wittenberg Nathan J.,
Oh SangHyun,
Cho NamJoon
Publication year - 2016
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201501914
Subject(s) - materials science , plasmon , surface modification , nanotechnology , particle (ecology) , nanoparticle , surface plasmon , plasmonic nanoparticles , optoelectronics , chemistry , oceanography , geology
A plasmonic nanohole sensor for virus‐like particle capture and virucidal drug evaluation is reported. Using a materials‐selective surface functionalization scheme, passive immobilization of virus‐like particles only within the nanoholes is achieved. The findings demonstrate that a low surface coverage of particles only inside the functionalized nanoholes significantly improves nanoplasmonic sensing performance over conventional nanohole arrays.