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Mesostructured TiO 2 Gated Periodic Mesoporous Organosilica‐Based Nanotablets for Multistimuli‐responsive Drug Release
Author(s) -
Wang Tao,
Guan Buyuan,
Wang Xue,
Li Xiang,
Zhang Ye,
Qiao ZhenAn,
Liu Yunling,
Huo Qisheng
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201501835
Subject(s) - mesoporous organosilica , materials science , nanoparticle , mesoporous material , nanotechnology , colloidal gold , titanium dioxide , chemical engineering , titanium , mesoporous silica , catalysis , organic chemistry , chemistry , composite material , metallurgy , engineering
A multistimuli‐responsive drug carrier is designed and successfully synthesized by self‐assembly of thiol‐modified periodic mesoporous organosilica (PMO) nanoparticles, coated gold nanoparticles (AuNPs), and mesostructured titanium dioxide (TiO 2 ). Dye‐loaded PMO‐Au@TiO 2 nanotablets are shown to respond to environmental changes (pH, temperature, and light) to achieve controlled release.