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Using Small Molecules to Prepare Vesicles with Designable Shapes and Sizes via Frame‐Guided Assembly Strategy
Author(s) -
Dong Yuanchen,
Yang Zhongqiang,
Liu Dongsheng
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201500240
Subject(s) - vesicle , generality , sodium dodecyl sulfate , amphiphile , nanotechnology , molecule , frame (networking) , membrane , amphiphilic molecule , self assembly , biophysics , chemistry , materials science , copolymer , computer science , organic chemistry , biochemistry , biology , psychology , telecommunications , psychotherapist , polymer
Following the principle of frame‐guided assembly (FGA) , a small amphiphilic molecule, sodium dodecyl sulfate, is shown to form vesicles with cholesterol as the leading hydrophobic group. These findings not only demonstrate the generality of the FGA but also provide a clue to understand the formation mechanism of the cell membrane, and even the origin of life.

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