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Nanoprobes: Inorganic–Organic Hybrid Nanoprobe for NIR‐Excited Imaging of Hydrogen Sulfide in Cell Cultures and Inflammation in a Mouse Model (Small 23/2014)
Author(s) -
Zhou Yi,
Chen Wangqiao,
Zhu Jixin,
Pei Wenbo,
Wang Chengyuan,
Huang Ling,
Yao Cheng,
Yan Qinyu,
Huang Wei,
Loo Joachim Say Chye,
Zhang Qichun
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201470146
Subject(s) - nanoprobe , hydrogen sulfide , excited state , materials science , photon upconversion , nanotechnology , near infrared spectroscopy , optoelectronics , nanoparticle , luminescence , optics , sulfur , physics , nuclear physics , metallurgy
Hydrogen sulfide (H 2 S) is an important gaseous signaling agent mediated by many physiological processes. However, current downconversion H 2 S probes are impractical for bioimaging due to the short tissue penetration of UV/visible light. As reported by J. S. C. Loo, Q. Zhang, and co‐workers on page 4874, a new design for the NIR‐excited imaging of H 2 S is developed by using coumarin‐hemicyanine (CHC1)‐modified upconversion nanophosphors. This work can be further developed as a diagnostic tool for the detection of H 2 S‐induced inflammatory diseases.