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Biosensors: Selective Detection of Target Proteins by Peptide‐Enabled Graphene Biosensor (Small 8/2014)
Author(s) -
Khatayevich Dmitriy,
Page Tamon,
Gresswell Carolyn,
Hayamizu Yuhei,
Grady William,
Sarikaya Mehmet
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201470047
Subject(s) - biosensor , graphene , peptide , nanotechnology , materials science , molecular recognition , biophysics , chemistry , biochemistry , molecule , biology , organic chemistry
Depiction of the graphene FET‐based bionanosensor functionalized with two engineered chimeric peptides, bio‐GrBP 5 , and SS‐GrBP 5 , which undergo spatially controlled self‐assembly on the sensor surface to bind to target protein (SA) with enhanced molecular selectivity. This novel peptide‐enabled graphene FET tool described on page 1505 by M. Sarikaya and co‐workers has potential to address a wide range of bio‐sensing problems, such as studying ligand‐receptor interactions and clinical detection of biomarkers.