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Encoded Particles: Fluorescence‐Encoded Gold Nanoparticles: Library Design and Modulation of Cellular Uptake into Dendritic Cells (Small 7/2014)
Author(s) -
RodriguezLorenzo Laura,
Fytianos Kleanthis,
Blank Fabian,
von Garnier Christophe,
RothenRutishauser Barbara,
PetriFink Alke
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201470043
Subject(s) - fluorescence , nanoparticle , colloidal gold , nanotechnology , biophysics , particle (ecology) , in vitro , materials science , green fluorescent protein , chemistry , biology , biochemistry , gene , physics , optics , ecology
Identification of parameters that modulate the cellular uptake into human dendritic cells in vitro is investigated through the fabrication of homo‐ (green spheres in the image) and hetero‐ (blue spheres) functional fluorescence encoded gold nanoparticles. As reported by L. Rodriguez‐Lorenzo, A. Petri‐Fink, and co‐workers on page 1341, the chemical modification of nanoparticle surfaces, for instance by attaching fluorescent dyes, can conceal fundamental particle properties and modulate cellular uptake.