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pH‐Responsive Capsules Engineered from Metal–Phenolic Networks for Anticancer Drug Delivery
Author(s) -
Ping Yuan,
Guo Junling,
Ejima Hirotaka,
Chen Xi,
Richardson Joseph J.,
Sun Huanli,
Caruso Frank
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201403343
Subject(s) - drug delivery , anticancer drug , nanotechnology , drug , computer science , targeted drug delivery , chemistry , combinatorial chemistry , materials science , pharmacology , medicine
A new class of pH‐responsive capsules based on metal–phenolic networks (MPNs) for anticancer drug loading, delivery and release is reported. The fabrication of drug‐loaded MPN capsules, which is based on the formation of coordination complexes between natural polyphenols and metal ions over a drug‐coated template, represents a rapid strategy to engineer robust and versatile drug delivery carriers.