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DNA‐Templated Silver Nanoclusters for Multiplexed Fluorescent DNA Detection
Author(s) -
Zhang Ying,
Zhu Changfeng,
Zhang Lei,
Tan Chaoliang,
Yang Jian,
Chen Bo,
Wang Lianhui,
Zhang Hua
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201402044
Subject(s) - nanoclusters , molecular beacon , fluorescence , nanotechnology , multiplexing , dna , beacon , computer science , computational biology , microfluidics , materials science , combinatorial chemistry , chemistry , biology , physics , oligonucleotide , telecommunications , biochemistry , quantum mechanics
Novel label‐free/conjugation‐free molecular beacons are designed based on DNA templated‐silver nanoclusters for multiplexed DNA detection. The assay is implemented in solution, which makes it easy for the in‐situ and real‐time analysis. This study demonstrates a new method for multiplexd detection of biological molecules by using fluorescent Ag nanocluster‐based molecular beacon probes.