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Pyramidal Sensor Platform with Reversible Chiroptical Signals for DNA Detection
Author(s) -
Yan Wenjing,
Xu Liguang,
Ma Wei,
Liu Liqiang,
Wang Libing,
Kuang Hua,
Xu Chuanlai
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201401641
Subject(s) - control reconfiguration , computer science , dissociation (chemistry) , dna , nanotechnology , limit (mathematics) , process (computing) , information retrieval , chemistry , materials science , embedded system , mathematics , biochemistry , operating system , mathematical analysis
A heterogeneous chiral sensor for DNA detection is demonstrated by post‐assembly system reconfiguration for two types of NPs pyramids. In the presence of target DNA, two types of NPs pyramids undergo dynamic reconfiguration or dissociation process which functions as an off‐on or on‐off switch towards CD signals changes. Under optimized conditions, the detection limit of this approach can reach to 3.4 aM with no involvement of amplification process.