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Injectable Microbeads with a Thermo‐Responsive Shell and a pH‐Responsive Core as a Dual‐Switch‐Controlled Release System
Author(s) -
Chiang WeiLun,
Hu YiChen,
Liu HungYi,
Hsiao ChunWen,
Sureshbabu Radhakrishnan,
Yang ChihMan,
Chung MinFan,
Chia WeiTso,
Sung HsingWen
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201400842
Subject(s) - dual (grammatical number) , microbead (research) , dual purpose , computer science , nanotechnology , core (optical fiber) , drug delivery , controlled release , content delivery , chemistry , materials science , computer network , engineering , telecommunications , biochemistry , mechanical engineering , art , literature
Treating inflammation with a dual‐switch‐controlled release system: The release of a drug from the developed microbead system occurs only in response to both an increase in local temperature and an acidic environmental pH. This dual‐switch‐controlled release system has the advantages of distinguishing between inflamed and healthy tissues to improve treatment efficacy.