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Stripe‐Patterned Thermo‐responsive Cell Culture Dish for Cell Separation without Cell Labeling
Author(s) -
Kumashiro Yoshikazu,
Ishihara Jun,
Umemoto Terumasa,
Itoga Kazuyoshi,
Kobayashi Jun,
Shimizu Tatsuya,
Yamato Masayuki,
Okano Teruo
Publication year - 2015
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201400787
Subject(s) - cell , adhesion , flow cytometry , nanotechnology , materials science , cell adhesion , computer science , chemistry , biology , microbiology and biotechnology , composite material , biochemistry
A stripe‐patterned thermo‐responsive surface is prepared to enable cell separation without labeling. The thermo‐responsive surface containing a 3 μm striped pattern exhibits various cell adhesion and detachment properties. A mixture of three cell types is separated on the patterned surface based on their distinct cell‐adhesion properties, and the composition of the cells is analyzed by flow cytometry.