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NIR‐Responsive Upconversion Nanoparticles Stimulate Neurite Outgrowth in PC12 Cells
Author(s) -
Guan Yijia,
Li Meng,
Dong Kai,
Ren Jinsong,
Qu Xiaogang
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201400612
Subject(s) - neurite , photon upconversion , nanoparticle , regeneration (biology) , materials science , nanotechnology , biophysics , rare earth , microbiology and biotechnology , chemistry , biology , optoelectronics , in vitro , biochemistry , luminescence , metallurgy
Nerve regeneration is of diagnostic importance in neuroscience in regards to the treatment of degenerative disease. Owing to the ability to release rare‐earth ions and produce ROS during upconversion process, upconversion nanoparticles are first reported for promoting neurite outgrowth. Different charged coating materials which play a critical role in cell attachment, can further lead to different effects on cell differentiation.