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Fiber‐Assisted Molding (FAM) of Surfaces with Tunable Curvature to Guide Cell Alignment and Complex Tissue Architecture
Author(s) -
Hosseini Vahid,
Kollmannsberger Philip,
Ahadian Samad,
Ostrovidov Serge,
Kaji Hirokazu,
Vogel Viola,
Khademhosseini Ali
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201400263
Subject(s) - curvature , computer science , molding (decorative) , materials science , nanotechnology , architecture , fiber , engineering drawing , mechanical engineering , composite material , engineering , geometry , mathematics , art , visual arts
A simple and robust method termed “fiber‐assisted molding (FAM)” is presented to create biomimetic three‐dimensional surfaces with controllable curvature and helical twist. The alignment of muscle fibrils and the assembly of helically patterned extracellular matrix by cells demonstrate the potential of this method for tissue engineering and other materials science applications.