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Upconversion: Tunable Near Infrared to Ultraviolet Upconversion Luminescence Enhancement in (α‐NaYF 4 :Yb,Tm)/CaF 2 Core/Shell Nanoparticles for In situ Real‐time Recorded Biocompatible Photoactivation (Small 19/2013)
Author(s) -
Shen Jie,
Chen Guanying,
Ohulchanskyy Tymish Y.,
Kesseli Samuel J.,
Buchholz Steven,
Li Zhipeng,
Prasad Paras N.,
Han Gang
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201370117
Subject(s) - photon upconversion , materials science , ultraviolet , nanoparticle , biocompatible material , in situ , luminescence , optoelectronics , core (optical fiber) , infrared , nanotechnology , near infrared spectroscopy , photochemistry , optics , chemistry , biomedical engineering , physics , medicine , organic chemistry , composite material
Upconversion nanoparticles (UCNPs) can convert tissue‐penetrable nearinfrared light into UV emission, making them promising as transducers for photoactivation in biology. However, the choice of the UV emitting UCNPs is limited and their NIR‐to‐UV efficiency is low. G. Han and co‐workers have addressed this issue by developing a family of CaF 2 ‐coated UCNPs with tunable UV enhancement. As reported on page 3213 , such design outperforms known optimal UCNPs and in situ realtime live‐cell photoactivation is recorded for the first time with such nanoparticles. This result is a potential game changer in photoactivation in living systems and a new tool for other biophotonic applications.