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Colorimetric Sensors: Distance‐Mediated Plasmonic Dimers for Reusable Colorimetric Switches: A Measurable Peak Shift of More than 60 nm (Small 2/2013)
Author(s) -
Guo Longhua,
Ferhan Abdul Rahim,
Chen Hailan,
Li Changming,
Chen Guonan,
Hong Seungpyo,
Kim DongHwan
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201370014
Subject(s) - plasmon , nanoparticle , materials science , nanotechnology , surface plasmon resonance , molecular switch , optoelectronics , chemistry , molecule , organic chemistry
The picture shows an approach to real‐time monitoring of single molecular binding events by the construction of a reconfigurable colorimetric DNA switch, described on page 234 . A significant spectral shift of over 60 nm is achievable from on–off switching. The switching is based on changing the interparticle distance between gold nanoparticles in dimers, actuated by targeted DNA binding. The extraordinary spectral shift allows the unaided eye to observe single‐target biomolecular binding events in real time under a darkfield microscope.