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Nanoprisms: Gold Nanoprisms as Optoacoustic Signal Nanoamplifiers for In Vivo Bioimaging of Gastrointestinal Cancers (Small 1/2013)
Author(s) -
Bao Chenchen,
Beziere Nicolas,
del Pino Pablo,
Pelaz Beatriz,
Estrada Giovani,
Tian Furong,
Ntziachristos Vasilis,
de la Fuente Jesus M.,
Cui Daxiang
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201370007
Subject(s) - photothermal therapy , materials science , in vivo , biocompatible material , nanotechnology , nanostructure , biomedical engineering , drug delivery , colloidal gold , preclinical imaging , photoacoustic imaging in biomedicine , nanoparticle , medicine , optics , physics , microbiology and biotechnology , biology
On page 68 , PEGylated gold nanoprisms are designed and prepared by J. M. de la Fuente, D. Cui, and co‐workers, with the aim to study the feasibility of using them as a novel contrast agent for the hybrid technique of optoacoustic imaging. The nanoprisms are imaged at different scales using different imaging modalities. They are confirmed as biocompatible, and selected colon cancer HT‐29 cells are used as research targets. Shown here is an in silico electron tomographic reconstruction of such gold nanostructures, which show promise for application in biomedical imaging, drug delivery, and photothermal therapy.