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DNA Origami Structures Directly Assembled from Intact Bacteriophages
Author(s) -
Nickels Philipp C.,
Ke Yonggang,
Jungmann Ralf,
Smith David M.,
Leichsenring Marc,
Shih William M.,
Liedl Tim,
Högberg Björn
Publication year - 2014
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201303442
Subject(s) - bacteriophage , dna , dna origami , nanotechnology , scaffold , computer science , computational biology , biology , materials science , genetics , database , gene , escherichia coli
Keeping it simple: a purified DNA single strand derived from bacteriophage M13 is typically used as scaffold material for DNA origami. This requires time‐consuming purification procedures to attain single‐stranded DNA. The direct use of intact bacteriophage particles as a scaffold source for DNA origami assemblies is reported.