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Light‐Induced Generation of Singlet Oxygen by Naked Gold Nanoparticles and its Implications to Cancer Cell Phototherapy
Author(s) -
Pasparakis George
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201301365
Subject(s) - singlet oxygen , photothermal therapy , colloidal gold , photochemistry , nanoparticle , plasmon , irradiation , materials science , photothermal effect , naked eye , surface plasmon resonance , oxygen , nanotechnology , chemistry , biophysics , optoelectronics , physics , organic chemistry , chromatography , nuclear physics , detection limit , biology
Generation of singlet oxygen by direct irradiation of naked gold nanoparticles is observed using either continuous wave or pulsed laser sources. The underlying mechanism involves plasmon‐ and hot‐electron‐mediated reaction pathways and 1 O 2 seems to significantly amplify the overall death rates during photothermal treatment of cancer cell lines in vitro.