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Programmable Imaging Amplification via Nanoparticle‐Initiated DNA Polymerization
Author(s) -
Chen Niancao,
Li Shihui,
Battig Mark R.,
Wang Yong
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201300806
Subject(s) - nanoparticle , polymerization , materials science , dna , monomer , nanotechnology , extracellular matrix , molecular imaging , biophysics , chemistry , polymer , biochemistry , biology , in vivo , composite material , microbiology and biotechnology
DNA growth on nanoparticles : Nanoparticle‐mediated molecular recognition and DNA polymerization are integrated for extracellular matrix (ECM) imaging via programmable signal amplification. By using DNA monomers labeled with identical or different imaging reagents, it is promising to achieve single‐ or multiple‐modality imaging of the ECM.