Premium
Biosensors: CdSe Quantum Dots Enhance Electrical and Electrochemical Signals of Nanogap Devices for Bioanalysis (Small 21/2012)
Author(s) -
Yu Yang,
Chen Xing,
Wei Yan,
Liu JinHuai,
Yu ShuHong,
Huang XingJiu
Publication year - 2012
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201290115
Subject(s) - quantum dot , streptavidin , bioanalysis , materials science , nanotechnology , biosensor , microelectrode , electrode , optoelectronics , nanoparticle , electron , chemistry , biotin , physics , biochemistry , quantum mechanics
Electrical and electrochemical signals are enhanced by CdSe quantum dots in a nanogap device for biotin–streptavidin sensing events, as demonstrated by X.‐J. Huang and co‐workers on page 3274 . By employing CdSe quantum dots, the ejection of the conduction‐band electrons to the streptavidin, with a concomitant transfer of electrons from the chain of biotin–streptavidin to the gold nanoparticle electrode, yields an enhanced current signal. This work could provide a massive multiplexing, high‐throughput, and high‐sensitivity technique for biosensing through the use of large microelectrode arrays.