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Lab‐on‐a‐Disc: Miniaturized Lab‐on‐a‐Disc (miniLOAD) (Small 12/2012)
Author(s) -
Glass Nick R.,
Shilton Richie J.,
Chan Peggy P. Y.,
Friend James R.,
Yeo Leslie Y.
Publication year - 2012
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201290065
Subject(s) - microfluidics , nanotechnology , mixing (physics) , materials science , capillary action , microfabrication , lab on a chip , centrifugal force , rotational speed , mechanical engineering , physics , engineering , fabrication , composite material , medicine , alternative medicine , pathology , quantum mechanics
The miniature Lab‐on‐a‐Disc (miniLOAD) concept shown in this image is the first completely miniaturized centrifugal microfluidics platform driven by solidstate actuation. Unlike its macroscopic Lab‐on‐a‐CD counterpart, which has gained considerable attention to date, but requires a large bench‐top rotational motor, the miniLOAD platform does not involve moving parts, is inexpensive, disposable, and considerably smaller. In this first proof‐of‐concept, its capability to drive capillary valving, mixing, and size‐based concentration/separation of aqueous particle suspensions in microchannels patterned on the disc is demonstrated.