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Biomimetic Methodology to Produce Polymeric Multilayered Particles for Biotechnological and Biomedical Applications
Author(s) -
Lima Ana Catarina,
Custódio Catarina A.,
AlvarezLorenzo Carmen,
Mano João F.
Publication year - 2013
Publication title -
small
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 3.785
H-Index - 236
eISSN - 1613-6829
pISSN - 1613-6810
DOI - 10.1002/smll.201202147
Subject(s) - nanotechnology , materials science , biomimetics , biomimetic materials , biochemical engineering , engineering
The production of multi‐compartmented particles for biomedical and biotechnological applications is challenging and the existing methods usually involve wet and aggressive conditions that compromise the encapsulation efficiency of bioactive agents and the viability of cells. Biomimetic superhydrophobic surfaces allow construction of concentric multilayered polymeric systems, adding sequential layers where molecules or cells may be separately confined in compartments with high efficiency.